The Air Carrier Access Act prohibits discrimination against disabled passengers and requires air carriers to provide certain accommodations for disabled passengers. The DOT has an extensive rule outlining the rights of passengers and the requirements of the airlines.
Generally, a disabled traveler does not need to notify the airline ahead of time. However, in instances where the airline must prepare for accommodations, the airline may require up to 48 hours’ notice. Examples include if the traveler requires a stretcher, use of the airline’s oxygen system, or use of an electric wheelchair on a flight of 60 seats or fewer.
Even when a passenger is not required to notify the airlines, it is best practice to notify the airline in advance when feasible.
An airline MAY require you to fly with an attendant if they reasonably find that you are unable to comprehend or respond to safety instruction or are unable to assist in your own evacuation from the plane in an emergency. The airline is not required to provide you with an attendant, but you may be able to find an off-duty crew member or a volunteer on your flight.
On double-aisle planes, at least one bathroom must be large enough to accommodate an attendant or aisle chair (on-board wheelchair). This accessible bathroom must offer privacy, must have a call button, and grab bars.
Airlines must offer, but the passenger need not accept, pre-boarding .